Autopsy and Case Reports
Autopsy and Case Reports
Clinical Case Report

Loss of an eye to mucormycosis following corticosteroid therapy for COVID-19

Mariana Gonçalves Rodrigues; William Kazunori Sekiguchi; Sérgio Gonçalves; Yuri Reis Casal; Fernando Pereira Frassetto; Vinicius Trindade Gomes da Silva; Marcelo Prudente do Espírito Santo; Marcello Mihailenko Chaves Magri

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Mucormycosis is a rare, sometimes severe fungal infection that has emerged as a possible complication of COVID-19. We report a case of a non-diabetic, apparently immunocompetent patient diagnosed with rhino-orbital-cerebral mucormycosis shortly after COVID-19 treatment with dexamethasone. The patient received optimized systemic antifungal therapy and extensive surgical treatment. So far, four months after the last hospital discharge, the patient has been in good general condition. This case is a dramatic reminder that beneficial corticosteroid therapy in general inevitably carries a risk of opportunistic infection, and corticosteroid therapy for COVID-19 risks orbital-rhinocerebral mucormycosis that clinicians should watch for with vigilance.


Keywords: Immunocompetence, SARS-CoV-2, Orbit


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3 Patel A, Agarwal R, Rudramurthy SM, et al. Multicenter epidemiologic study of coronavirus disease-associated mucormycosis, India. Emerg Infect Dis. 2021;27(9):2349-59. PMid:34087089.

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