Autopsy and Case Reports
https://www.autopsyandcasereports.org/article/doi/10.4322/acr.2021.377
Autopsy and Case Reports
Clinical Case Report and Review

Endobronchial lipoma

Lakshitha Anbazhakan; Asad Ullah; Rohit Munagala; Rabih Bechara; Islam Elhelf; Nikhil Patel; Nagla Abdel Karim

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Abstract

Endobronchial lipomas are rare benign lung tumors that can cause bronchial obstruction and parenchymal damage. While an uncommon etiology, they are often misdiagnosed due to a clinical presentation similar to obstructive pulmonary pathologies such as COPD and asthma. Upon review of English-language literature, under 50 cases of endobronchial lipomas were documented in the prior 10 years (2011-2021). There are no clear guidelines regarding the management of this particular entity, but typically interventional debulking is the treatment of choice. Here we present another unique case of endobronchial lipoma along with our diagnostic and therapeutic methodology. The patient underwent bronchoscopic debulking via a cryotherapy probe. Based on the histopathologic analysis, a diagnosis of endobronchial lipoma was made. Endobronchial lipomas must remain in any clinician’s differential when a patient presents with dyspnea. We report the unique location of this lipoma based on our literature review and the importance of investigating endobronchial lesions due to a possible diagnosis of endobronchial lipoma.

Keywords

Lipoma, Bronchoscopy, Airway Obstruction

References

1 Griffeth EM, Whitson B, Huard D, Brown BR. Endobronchial lipoma: case report and literature review. Am J Med Sci. 2021;361(1):111-7. http://dx.doi.org/10.1016/j.amjms.2020.07.010. PMid:32807376.

2 Rodrigues AJ, Coelho D, Dias SA Jr, Jacomelli M, Scordamaglio PR, Figueiredo VR. Minimally invasive bronchoscopic resection of benign tumors of the bronchi. J Bras Pneumol. 2011;37(6):796-800. http://dx.doi.org/10.1590/S1806-37132011000600014. PMid:22241038.

3 Dy RV, Patel S, Harris K, Mador MJ. Endobronchial lipoma causing progressive dyspnea. Respir Med Case Rep. 2017;22:95-7. http://dx.doi.org/10.1016/j.rmcr.2017.07.002. PMid:28736696.

4 Liew CJ, Tham KY, Poh AC, Tee A. Endobronchial lipoma. Singapore Med J. 2017;58(8):510-1. http://dx.doi.org/10.11622/smedj.2017015. PMid:28261742.

5 Eren F, Candan T, Eren B, Comunoglu N, Comunoglu C. Endobronchial lipoma. J Pak Med Assoc. 2013;63(6):784-5. PMid:23901688.

6 Leichtle SW, McCabe V, Gupta A. Obstructing endobronchial lipoma. Ann Thorac Surg. 2014;97(2):714. http://dx.doi.org/10.1016/j.athoracsur.2013.06.095. PMid:24484822.

7 Guelbenzu Zazpe JJ, Ramírez Gil E, Vilá Mayo E. Talking about endobronchial lipoma. Arch Bronconeumol. 2015;51(5):251-2. http://dx.doi.org/10.1016/j.arbres.2014.06.002. PMid:25059588.

8 Harris K, Dhillon S, Huang M, Kumar A, Qiu J. Endobronchial lipoma: bronchoscopy, imaging and pathology. Ther Adv Respir Dis. 2014;8(5):162-4. http://dx.doi.org/10.1177/1753465814548190. PMid:25234277.

9 Sivapalan P, Gottlieb M, Christensen M, Clementsen PF. An obstructing endobronchial lipoma simulating COPD. Eur Clin Respir J. 2014;1(1):25664. http://dx.doi.org/10.3402/ecrj.v1.25664.

10 Azhar W, Zaidi F, Hannan A. Whistling lipoma: bronchial obstruction caused by a lipoma. Cureus. 2020;12(3):e7167. http://dx.doi.org/10.7759/cureus.7167. PMid:32257709.

11 Triviño A, Mora-Cabezas M, Vallejo-Benitez A, García-Escudero A, González-Cámpora R. Endobronchial lipoma: a rare cause of bronchial occlusion. Arch Bronconeumol. 2013;49(11):494-6. http://dx.doi.org/10.1016/j.arbr.2013.09.007. PMid:23680317.

12 Cao D, Sun Y, Yang S. Endobronchial lipoma: an unusual cause of bronchial obstruction. Case Rep Med. 2011;2011:939808. http://dx.doi.org/10.1155/2011/939808. PMid:21969834.

13 Sacristán Bou L, Fernández Robledo E, Peña Blas F. Endobronchial lipoma: an unusual cause of bronchial obstruction. Arch Bronconeumol. 2014;50(2):78-9. http://dx.doi.org/10.1016/j.arbr.2014.01.009. PMid:24119688.

14 Rooijakkers M, Wynants J, Aumann J. Endobronchial lipoma, an extremely rare benign tumour of the lung, mimicking asthma bronchiale. Acta Clin Belg. 2014;69(1):74-5. http://dx.doi.org/10.1179/0001551213Z.00000000010. PMid:24635404.

15 Shinohara S, Hanagiri T, Takenaka M, et al. An endobronchial lipoma successfully resected by high-frequency electric snare: a report of 2 cases. J Bronchology Interv Pulmonol. 2012;19(1):68-71. http://dx.doi.org/10.1097/LBR.0b013e31823fa944. PMid:23207269.

16 Alves GRT, Pasquali M, de Silva RV, Haygert CJP. An infrequent cause of persistent cough: endobronchial lipoma. Ann Saudi Med. 2013;33(6):636-7. http://dx.doi.org/10.5144/0256-4947.2013.636. PMid:24413877.

17 Lamprecht B, Hutarew G, Porsch P, Wegleitner B, Studnicka M. Successful bronchoscopic cryorecanalization in a case of endobronchial lipoma. Diagn Ther Endosc. 2011;2011:845686. http://dx.doi.org/10.1155/2011/845686. PMid:21789029.

18 Galvez C, Sesma J, Bolufer S, et al. Single-incision video-assisted anatomical segmentectomy with handsewn bronchial closure for endobronchial lipoma. Ann Transl Med. 2016;4(15):284. http://dx.doi.org/10.21037/atm.2016.07.25. PMid:27570778.

19 Wang H, Du Z, Li A, Song J. Surgical treatment of an endobronchial lipoma obstructing the right upper bronchus: imaging features with pathological correlation. Pak J Med Sci. 2013;29(6):1447-9. http://dx.doi.org/10.12669/pjms.296.3708. PMid:24550972.

20 Madan K, Agarwal R, Bal A, Gupta D. Bronchoscopic management of a rare benign endobronchial tumor. Rev Port Pneumol. 2012;18(5):251-4. http://dx.doi.org/10.1016/j.rppneu.2012.02.003. PMid:22463875.

21 Chen H, Wang S, Zhou J, Liu S. Endobronchial lipoma presenting as recurrent pneumonia. QJM. 2020;113(11):834-5. http://dx.doi.org/10.1093/qjmed/hcaa087. PMid:32145027.

22 Pavlov PV, Kiryukhin AP, Puzakov KB, Rzayev RT, Derinov AA. Endobronchial lipoma: a rare cause of subsegmental bronchial obstruction. Respirol Case Rep. 2019;8(1):e00505. http://dx.doi.org/10.1002/rcr2.505. PMid:31788313.

23 Yazawa T, Igai H, Matsuura N, Ohsawa F, Kamiyoshihara M. Removal of an endobronchial lipoma via uniportal thoracoscopic right basal segmentectomy. Surg Case Rep. 2020;6(1):212. http://dx.doi.org/10.1186/s40792-020-00973-z. PMid:32804314.

24 Lanotte S, Frognier R, Van Cutsem O, Mailleux P. Bronchial lipoma: an unusual cause of pleural empyema. JBR-BTR. 2015;98(2):88-90. http://dx.doi.org/10.5334/jbr-btr.773. PMid:30394415.

25 Bansal S, Utpat K, Desai U, Joshi JM. Endobronchial lipoma with tuberculosis: a solitary coetaneousness. Lung India. 2018;35(1):90-1. http://dx.doi.org/10.4103/lungindia.lungindia_319_17. PMid:29319046.

26 Wang Y, Teng Y, Li J, Lin T, Lu N, Yuan Y. Endobronchial lipoma with tracheobronchial aspergillosis: a case report. Medicine (Baltimore). 2021;100(11):e24381. http://dx.doi.org/10.1097/MD.0000000000024381. PMid:33725932.

27 Zhao S, Shui Y, Dai Z. Multiple endo bronchial lipoma: a rare case report. BMC Pulm Med. 2020;20(1):251. http://dx.doi.org/10.1186/s12890-020-01287-4. PMid:32962678.

28 Nussbaumer-Ochsner Y, Rassouli F, Uhlmann F, Thurnheer R. Endobronchial lipoma mimicking bronchial carcinoid tumour. Thorax. 2015;70(8):809. http://dx.doi.org/10.1136/thoraxjnl-2015-206923. PMid:25828429.

29 Yun SC, Na MJ, Choi E, et al. Successful removal of endobronchial lipoma by flexible bronchoscopy using electrosurgical snare. Tuberc Respir Dis (Seoul). 2013;74(2):82-5. http://dx.doi.org/10.4046/trd.2013.74.2.82. PMid:23482342.

30 Flores-Franco RA, González-Calzadillas LF, Cota-Castro S. Successful endoscopic resection of an endobronchial lipoma using a percutaneous gastrostomy snare device. Arch Bronconeumol. 2018;54(4):235-6. http://dx.doi.org/10.1016/j.arbres.2017.10.004. PMid:29198487.

31 Jaurrieta Largo S, de Vega Sánchez B, Disdier Vicente C. Endobronchial lipoma excision by cryotherapy and flexible bronchoscopy. Exéresis mediante crioterapia y broncoscopia flexible de lipoma endobronquial. Arch Bronconeumol. 2019;55(9):490. http://dx.doi.org/10.1016/j.arbres.2019.02.008. PMid:30879877.

32 On R, Kushima H, Ishii H, Watanabe K. Endobronchial lipoma: the diagnostic benefit of computed tomography findings. Intern Med. 2018;57(2):285-6. http://dx.doi.org/10.2169/internalmedicine.9289-17. PMid:29033444.

33 Pollefliet C, Peters K, Janssens A, et al. Endobronchial lipomas: rare benign lung tumors, two case reports. J Thorac Oncol. 2009;4(5):658-60. http://dx.doi.org/10.1097/JTO.0b013e31819c9a59. PMid:19395910.

34 Huisman C, van Kralingen KW, Postmus PE, Sutedja TG. Endobronchial lipoma:a series of three cases and the role of electrocautery. Respiration. 2000;67(6):689-92. http://dx.doi.org/10.1159/000056302. PMid:11124655.
 


Submitted date:
11/22/2021

Accepted date:
04/07/2022

Publication date:
05/02/2022

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