Autopsy and Case Reports
https://www.autopsyandcasereports.org/article/doi/10.4322/acr.2020.216
Autopsy and Case Reports
Clinical Case Report and Review

Ossifying fibromyxoid tumor of the oral cavity: rare case report and long-term follow-up

Maria Eduarda Pérez-de-Oliveira; Thayná Melo de Lima Morais; Márcio Ajudarte Lopes; Oslei Paes de Almeida; Willie F. P. van Heerden; Pablo Agustin Vargas

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Abstract

ABSTRACT: Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal soft tissue benign neoplasm with an uncertain line of differentiation, which arises most frequently in extremities. The head and neck region involvement is uncommon, with only ten intraoral cases published in the English-language literature. One additional case of OFMT is reported here, including a literature review of intraoral reported cases. A 45-year-old female patient presented a painless nodule involving the buccal mucosa of approximately two years duration, measuring nearly 1.3 cm in maximum diameter. The main histopathological features include ovoid to round cells embedded in a fibromyxoid matrix with a perpheral shell of lamellar bone. Immunohistochemically, the tumor showed immunoreactivity for vimentin and S100. No recurrence has been detected after 7 years of follow-up.

Keywords

head and neck neoplasms, soft tissue neoplasms, mouth

References

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Publication date:
12/08/2020

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