Autopsy and Case Reports
https://www.autopsyandcasereports.org/article/doi/10.4322/acr.2020.202
Autopsy and Case Reports
Clinical Case Report

Treatment of radiation-induced brachial plexopathy with omentoplasty

Adilson José Manuel de Oliveira; João Paulo de Souza Castro; Luciano Henrique Foroni; Mário Gilberto Siqueira; Roberto Sérgio Martins

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Abstract

Radiation-induced brachial plexus neuropathy (RIBPN) is a rare and delayed non-traumatic injury to the brachial plexus, which occurs following radiation therapy to the chest wall, neck, and/or axilla in previously treated patients with cancer. The incidence of RIBPN is more common in patients treated for carcinoma of the breast and Hodgkin lymphoma. With the improvement in radiation techniques, the incidence of injury to the brachial plexus following radiotherapy has dramatically reduced. The currently reported incidence is 1.2% in women irradiated for breast cancer. The progression of symptoms is gradual in about two-thirds of cases; the patients may initially present with paresthesia followed by pain, and later progress to motor weakness in the affected limb. We present the case of a 68-year-old female patient with breast cancer submitted to surgery, chemotherapy, and radiotherapy in the year 2000. Eighteen years later, she developed symptoms and signs compatible with RIBPN and was successfully submitted to omentoplasty for pain control. Omentoplasty is an alternative treatment for RIBPN refractory to conservative treatment, which seems to be effective in improving neuropathic pain. However, postoperative worsening of the motor strength is a real possibility, and all candidates for this type of surgery must be informed about the risk of this complication.

Keywords

Brachial Plexus Neuropathies, Radiation Injuries, Pain, Intractable, Neurosurgery

References

Bowen BC, Verma A, Brandon AH, Fiedler JA. Radiation-induced brachial plexopathy: MR and clinical findings.

AJNR Am J Neuroradiol. 1996;17(10):1932-6. [PMID:8933882]

Stoll BA, Andrews JT. Radiation-induced peripheral neuropathy.

BMJ. 1966;1(5491):834-7. [https://doi.org/10.1136/bmj.1.5491.834]. [PMID:20790877]

Schierle C, Winograd JM. Radiation-induced brachial plexopathy: review. Complication without a cure.

J Reconstr Microsurg. 2004;20(2):149-52. [https://doi.org/10.1055/s-2004-820771]. [PMID:15011123]

Fathers E, Thrush D, Huson SM, Norman A. Radiation-induced brachial plexopathy in women treated for carcinoma of the breast.

Clin Rehabil. 2002;16(2):160-5. [https://doi.org/10.1191/0269215502cr470oa]. [PMID:11911514]

Ko K, Sung DH, Kang MJ, et al. Clinical, electrophysiological findings in adult patients with non-traumatic plexopathies.

Ann Rehabil Med. 2011;35(6):807-15. [https://doi.org/10.5535/arm.2011.35.6.807]. [PMID:22506209]

Killer HE, Hess K. Natural history of radiation-induced brachial plexopathy compared with surgically treated patients.

J Neurol. 1990;237(4):247-50. [https://doi.org/10.1007/BF00314628]. [PMID:2391547]

Olsen NK, Pfeiffer P, Johannsen L, Schrøder H, Rose C. Radiation-induced brachial plexopathy: neurological follow-up in 161 recurrence-free breast cancer patients.

Int J Radiat Oncol Biol Phys. 1993;26(1):43-9. [https://doi.org/10.1016/0360-3016(93)90171-Q]. [PMID:8387067]

Pavi J, Denekamp J, Letschert J. LENT-SOMA scales for all anatomic sites.

Int J Radiat Oncol Biol Phys. 1995;31(5):1049-91. [https://doi.org/10.1016/0360-3016(95)90159-0]. [PMID:7713776]

Gosk J, Rutowski R, Reichert P, Rabczyński J. Radiation-induced brachial plexus neuropathy-aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment.

Folia Neuropathol. 2007;45(1):26-30. [PMID:17357008]

Gillette EL, Mahler PA, Powers BE, Gillette SM, Vujaskovic Z. Late radiation injury to muscle and peripheral nerves.

Int J Radiat Oncol Biol Phys. 1995;31(5):1309-18. [https://doi.org/10.1016/0360-3016(94)00422-H]. [PMID:7713790]

Johansson S, Svensson H, Denekamp J. Timescale of evolution of late radiation injury after postoperative radiotherapy of breast cancer patients.

Int J Radiat Oncol Biol Phys. 2000;48(3):745-50. [https://doi.org/10.1016/S0360-3016(00)00674-X]. [PMID:11020571]

Warade AC, Jha AK, Pattankar S, Desai K. Radiation-induced brachial plexus neuropathy: a review.

Neurol India. 2019;67(Suppl):S47-52. [https://doi.org/10.4103/0028-3886.250704]. [PMID:30688233]

Narakas AO. Operative treatment for radiation-induced and metastatic brachial plexopathy in 45 cases, 15 having an omentoplasty.

Bull Hosp Jt Dis Orthop Inst. 1984;44(2):354-75. [PMID:6099180]

Brunelli G, Brunelli F. Surgical treatment of actinic brachial plexus lesions: free microvascular transfer of the greater omentum.

J Reconstr Microsurg. 1985;1(3):197-200. [https://doi.org/10.1055/s-2007-1007074]. [PMID:4057159]

Uhlschmid G, Clodius L. A new use for the freely transplanted omentum. Management of a late radiation injury of the brachial plexus using freely transplanted omentum and neurolysis.

Chirurg.1978;49(11):714-18. [PMID:720164].

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Submitted date:
04/24/2020

Accepted date:
05/24/2020

Publication date:
09/02/2020

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