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Autopsy and Case Reports
Article / Clinical Case Report

Atypical behavioral and psychiatric symptoms: Neurosyphilis should always be considered

Lucas Lonardoni Crozatti; Marcelo Houat de Brito; Beatriz Noele Azevedo Lopes; Fernando Peixoto Ferraz de Campos

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Syphilis still remains a major health concern worldwide because of the possibility of serious medical and psychological consequences, long-term disability, and death. Neurosyphilis (NS) may occur at any stage of infection. Its clinical presentation has been changing over recent years including­ psychiatric and neurocognitive symptoms. Several recent studies have described cases with these symptoms as the principal signs of NS. We present the case of neurosyphilis with a psychiatric presentation characterized by mood disturbance and auditory and visual hallucinations.


Neurosyphilis, Depression, Hallucinations, Diagnosis, Cerebrospinal fluid


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