Giant keratocystic odontogenic tumor: a challenging diagnosis
Rachna Kaushik, Kumar Pushpanshu, Silky Rajesh Punyani, Vineet Raj
Abstract
The keratocystic odontogenic tumor, although a benign lesion, is peculiarly aggressive with a high recurrence rate. Its involvement with the maxillary antrum is atypical. We report the unusual case of a 20-year-old male patient with an extensive antral tumor associated with an impacted third molar, which was initially misdiagnosed as a dentigerous cyst. Clinical, radiographic, and histopathologic aspects were analyzed to provide useful information for the correct diagnosis, treatment, and prognosis within a multidisciplinary approach.
Keywords
References
1. Kwon HI, Lim WB, Kim JS, et al. Odontogenic Keratocyst associated with an ectopic tooth in the Maxillary sinus: a report of two cases and a review of the literature. Korean J Pathol. 2011;45(Suppl 1):S5-10. http://dx.doi.org/10.4132/KoreanJPathol.2011.45.S1.S5.
2. Chaudhary S, Sinha A, Barua P, Mallikarjuna R. Keratocystic odontogenic tumour (KCOT) misdiagnosed as a dentigerous cyst. BMJ Case Rep. 2013;2013 PMid:23429028.
3. El-Hajj G, Anneroth G. Odontogenic keratocysts: a retrospective clinical and histologic study. Int J Oral Maxillofac Surg. 1996;25(2):124-9. http://dx.doi.org/10.1016/S0901-5027(96)80057-9. PMid:8727585.
4. Cakur B, Miloglu O, Yolcu U, Göregen M, Gürsan N. Keratocystic odontogenic tumor invading the right maxillary sinus: a case report. J Oral Sci. 2008;50(3):345-9. http://dx.doi.org/10.2334/josnusd.50.345. PMid:18818473.
5. Grasmuck EA, Nelson BL. Keratocystic odontogenic tumor. Head Neck Pathol. 2010;4(1):94-6. http://dx.doi.org/10.1007/s12105-009-0146-x. PMid:20237995.
6. Sánchez-Burgos R, González-Martín–Moro J, PérezFernández E, Burgueño-García M. Clinical, radiological and therapeutic features of keratocystic odontogenic tumours: a study over a decade. J Clin Exp Dent. 2014;6(3):e259-64. http://dx.doi.org/10.4317/jced.51408. PMid:25136427.
7. Byun JH, KangYH, ChoiMJ, Park BW. Expansile keratocystic odontogenic tumor in the maxilla: immunohistochemical studies and review of literature. J Korean Assoc Oral Maxillofac Surg. 2013;39(4):182-7. http://dx.doi. org/10.5125/jkaoms.2013.39.4.182. PMid:24471040.
8. Gupta A, Rai B, Nair MA, Bhut MK. Keratocystic odontogenic tumor with impacted maxillary third molar involving the right maxillary antrum: an unusual case report. Indian J Dent Res. 2011;22(1):157-60. http://dx.doi.org/10.4103/0970-9290.79984. PMid:21525696.
9. Regezi JA, Sdubba JJ. Oral pathology: clinical-pathologic correlations. 2nd ed. Philadelphia: W.B. Saunders Company; 1993. p. 337-341.
10. R.A .Cawson, E.W.Odell. Cawson’s essentials of oral pathology and oral medicine. 8th ed. Edinburgh: Churchill Livingstone; 2008.
11. Scharffetter K, Balz-Herrmann C, Lagrange W, Koberg W, Mittermayer C. Proliferation kinetics-study of the growth of keratocysts: morpho-functional explanation for recurrences. J Craniomaxillofac Surg. 1989;17(5):226-33. http://dx.doi.org/10.1016/S1010-5182(89)80074-5. PMid:2668340.
12. Makowski GJ, McGuff S, Van Sickels JE. Squamous cell carcinoma in a maxillary odontogenic keratocyst. J Oral Maxillofac Surg. 2001;59(1):76-80. http://dx.doi.org/10.1053/joms.2001.19297. PMid:11152194.
13. Haring JI, Van Dis ML. Odontogenic keratocysts: a clinical, radiographic, and histopathologic study. Oral Surg Oral Med Oral Pathol. 1988;66(1):145-53. http://dx.doi.org/10.1016/0030-4220(88)90082-5. PMid:2457195.
14. Koçak-Berberoğlu H, Çakarer S, Brkić A, Gürkan-Koseoglu B, Altuğ-Aydil B, Keskin C. Three-dımensıonal cone- beam computed tomography for dıagnosıs of keratocystıc odontogenıc tumours; evaluatıon of four cases. Med Oral Patol Oral Cir Bucal. 2012;17(6):e1000-5. http://dx.doi.org/10.4317/medoral.17629. PMid:22549670.
15. DelBalso AM. An approach to the diagnostic imaging of jaw lesions, dental implants, and the temporomandibular joint. Radiol Clin North Am. 1998;36(5):855-90, vi. http://dx.doi.org/10.1016/S0033-8389(05)70067-1. PMid:9747192.
Publication date:
09/29/2016
Facebook
Google+
Twitter
LinkedIn
Mendeley
StumbleUpon
CiteULike
Reddit
Email